My lab investigates new high throughput functional genomics methods to study gene regulation in the major human malaria parasite species (P. falciparum and P. vivax) and the zoonotic species, P. knowlesi. In particular, my laboratory generates large genome-wide data sets using next generation sequencing and proteomics technologies along with novel computational biology approaches to better understand the role of epigenomics and chromatin structure in transcriptional regulation and identify key molecular mechanisms underlying parasites life cycle development.

Prof. Karine Le Roch