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Multiple dimensions of epigenetic gene regulation in malaria parasites -Transcriptional regulation via histone modifications, nucleosome positioning and nuclear architecture.

My lab investigates new high throughput functional genomics methods to study gene regulation in the major human malaria parasite species (P. falciparum and P. vivax) and the zoonotic species, P. knowlesi. In particular, my laboratory generates large genome-wide data sets using next generation sequencing and proteomics technologies along with novel computational biology approaches to better...

Microbial eukaryotes in marine sediments: linking molecules with morphology in the -Omics age

Microbial eukaryotes (organisms <1mm, such as nematodes, fungi, protists, and other ‘minor’ metazoan phyla) are abundant and ubiquitous in marine sediments, performing key functions such as nutrient cycling and sediment stability in marine habitats. Yet, their unexplored diversity represents one of the major challenges in biology and currently limits our capacity to understand, mitigate and...